It is expected to reopen later Friday once cleanup efforts are complete.
They will be paving at the intersection of Route 20 and Brickyard Rd. in the morning.
The project includes milling and paving 4.4 miles of roadway from Route 6 to Route 98.
The bridge goes over Shirley Run.
Work includes resurfacing the existing deck and parts of the road leading up to the bridge, in addition to other minor structural repairs.
The project includes paving of 2.4 miles of roadway on and Route 20 (Ridge Road/Main St.) from Chestnut St. to Imperial Parkway.
It is closed from Bowmantown Rd. to Albion Rd. due to damage to the railroad bridge over the roadway.
PennDOT said it is working to treat roadways in the area.
The street was closed from Ash St. to the intersection of E. 28th St./Old French Rd.
The bridge closed in June for rehabilitation work on the piers, abutment walls and deck.
The roadway was set to be closed last weekend, but the closure was delayed due to equipment-related issues.
It comes after a routine inspection uncovered deterioration to the 32-foot concrete structure.Â
Drivers in downtown Erie will see several street closings for this weekend's CelebrateErie, which runs Friday through Sunday.
Left turns from Route 6N to Route 99 will not be permitted starting Monday.
The paving, which is scheduled to start Monday, will be done from Thatcher Ln. near Country Fair to Dollar General near Railroad St.
PennDOT said drivers may also see rolling closures and should expect delays during these times.
All lanes will be closed from McClelland Ave. to the Bayfront Connector from 8 a.m. to 4 p.m.
Here's a look at the maintenance work scheduled by Pennsylvania Department of Transportation (PennDOT) for the upcoming week.
Drivers will see periodic rolling stops on I-90 eastbound and the Interstate 79 ramps to I-90 eastbound between 7Â a.m. to 7 p.m. Tuesday and Wednesday. There is also a lane closure near the bridge.
There will be periodic rolling stops on I-90 westbound and the Interstate 79 ramps to I-90 westbound between 7Â a.m. and 7 p.m. on April 19 and 20. There will also be a lane closure near the bridge.
Drivers are being detoured onto I-86 eastbound to Route 89 northbound to I-90.
The closure forced drivers in Pennsylvania who were heading to New York to use Interstate 86 and other routes.
All vehicle restrictions have been removed, and the speed limits have been restored on Interstates 90 and 86.
PennDOT will continue to treat roadways in the area until they are clear.
The closure is expected to remain in place overnight.
Both the eastbound and westbound lanes between State Routes 7 and 11 were shut down for more than seven hours starting Thursday morning.
It will be closed near W. 38th St. in the area of the bridge crossing Walnut Creek from 9 a.m. to approximately 2 p.m.
It will be held Monday, Nov. 21, from 5 to 7 p.m. at the Erie County Technical School cafeteria.
The changes are part of a project designed to improve safety for pedestrians and cyclists and allow for safer and more efficient traffic flow along three miles of 12th Street from Interstate 79 to the Bayfront Connector, according to PennDOT.
A detour using Route 215 northbound to Route 20 eastbound to Route 18 southbound has been posted.